Aggressive form of HIV discovered in Cuba
Researchers from Cuba and Belgium reported a recombinant form of the Human Immunodeficiency Virus (CRF-19) in Cuba that appears to progress much more rapidly than other forms of the
virus, causing AIDS within about 3 years. (Compared to 10 years or more with most HIV infections.) “It has been speculated that inter-subtype recombination may give rise to more pathogenic strains…”
This reports presents evidence this is true. Patients infected with this virus had significantly faster depletion of CD4 lymphocytes.
Kouri V, Khouri R, et al. CRF19_cpx is an Evolutionary fit HIV-1 Variant Strongly Associated With Rapid Progression
to AIDS in Cuba. EBioMedicine. 2015.
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